This product has been shown to be effective for the vaccination of healthy pregnant cattle to provide passive immunity in calves against disease caused by bovine rotavirus and bovine coronavirus. Vaccinate pregnant cattle to provide scour protection to calves through the colostrum. Give 2 ml IM, 8-16 weeks prior to calving. Repeat 4 weeks prior to calving. Booster annually, 8-10 weeks prior to calving.